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Alexandria Soto, B.S., B.A.

Alex began working in the Marsh Lab in March 2018, as an undergraduate neuroscience and medical humanities double major at Johns Hopkins. Alex worked on investigating the relationship between changes on nailbed capillaroscopy and degree of white matter disease on MRI in a population with cerebrovascular disease. She is currently working as a postgraduate research associate at the neurology department at Yale University.


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Adam Chang, B.S.

Adam began doing research with the Marsh lab in the summer of 2017 as a student at Johns Hopkins University. His first project examined the need for ICU monitoring after treatment with intravenous tissue plasminogen activator (IV tPA). Treatment with IV tPA may result in symptomatic intracranial hemorrhage, a life-threatening complication. The current standard of care places these patients under 24 hours of ICU monitoring post-treatment, which is resource-intensive. Results of the study showed that the majority of sICH occurred within the first few hours of treatment, and that 24 hours of ICU monitoring may not be required for most patients. His second project studied the effects of IV tPA on the conversion of proximal large-vessel occlusions, and the effects that this has on intra-arterial thrombectomy, a catheter clot removal procedure, as well as overall clinical outcomes.

Adam graduated from Johns Hopkins University in 2019 and is currently attending medical school.

Publication

Chang A, Llinas EJ, Chen K, Llinas RH, Marsh EB. Shorter intensive care unit stays?: The majority of post-intravenous tPA (tissue-type plasminogen activator) symptomatic hemorrhages occur within 12 hours of treatment. Stroke 2018;49(6):1521-1524.
Click to read article


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Edward Llinas

Edward worked in the Marsh lab during the summers of 2018 and 2019 investigating the timing of symptomatic hemorrhage after treatment with IV tPA. He is an undergraduate student at Duke University. 

Publication

Chang A, Llinas EJ, Chen K, Llinas RH, Marsh EB. Shorter intensive care unit stays?: The majority of post-intravenous tPA (tissue-type plasminogen activator) symptomatic hemorrhages occur within 12 hours of treatment. Stroke 2018;49(6):1521-1524.
Click to read article


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Karen Chen, B.A.

Karen started out doing research in the Marsh lab as an undergraduate for two summers in 2014 and 2016. She graduated from Case Western Reserve University with her Bachelors of Arts in Biology and Psychology in 2017, and is now attending medical school at Penn State College of Medicine.

Her first project examined the added utility of CTA in assessing dizzy patients for posterior circulation ischemia. Results showed that the presence of calcium on CTA does not significantly increase the ability to predict stroke; a vascular risk assessment and neurological exam should remain the standard evaluation for risk-stratifying ischemia in dizzy patients. Her second study investigated the factors associated with post-stroke fatigue and how they evolve from the early to chronic phases of recovery.

Publications

  1. Chang A, Llinas EJ, Chen K, Llinas RH, Marsh EB. Shorter intensive care unit stays?: The majority of post-intravenous tPA (tissue-type plasminogen activator) symptomatic hemorrhages occur within 12 hours of treatment. Stroke 2018;49(6):1521-1524. Click to read article

  2. Marsh EB, Lawrence E, Hillis AE, Chen K, Gottesman RF, Llinas RH. Pre-stroke employment results in better patient-reported outcomes after minor stroke. Clinical Neurology and Neurosurgery 2018;165:38-42. Click to read article

  3. Chen K, Schneider ALC, Llinas RH, Marsh EB. Keep it simple: vascular risk factors and focal exam findings correctly identify posterior circulation ischemia in “dizzy” patients. BMC Emergency Medicine 2016;16(1):8-16. Click to read article


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Demitre Gweh, B.S.

Demitre began working in the Marsh lab in November 2017 and graduated from Johns Hopkins University with a B.S. in Neuroscience in 2018. In the lab, Demitre assessed the prevalence of headaches in patients following aneurysm procedures.


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Courtney Whilden

Courtney is an undergraduate neuroscience student at Johns Hopkins, and she began working at the Marsh lab in August 2017. She worked on a study that addressed the relationship between patient-reported outcomes of recovery and objective measurements of cognitive recovery after stroke. Courtney has also assisted in the implementation of patient surveys in the clinic that assess patient expectations for recovery.

Courtney currently works in the Brown Lab, investigating circuits of the neocortex. She plans on graduating in 2020 and going on to pursue her Ph.D. in Neuroscience.


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Martin Chacon-Portillo, M.D.

Dr. Martin Chacon-Portillo spent nearly a year with the Marsh lab investigating the association between cerebral microbleeds and hemorrhage after IV tPA and showed that the risk for symptomatic hemorrhage was low. He is now a medical resident at the University of Arizona.

Publication

Chacon-Portillo MA, Llinas RH, Marsh EB. Cerebral microbleeds shouldn't dictate treatment of acute stroke: a retrospective cohort study evaluating risk of intracerebral hemorrhage. BMC Neurology 2018;18(1):33.
Click to read article


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Richa Sharma, M.D., M.P.H.

Dr. Richa Sharma was part of the Marsh lab during her Neurology Residency at Johns Hopkins. Her areas of interest included the role of collaterals in predicting outcome and post-stroke cognitive impairment. She is currently a Stroke Fellow at the Massachusetts General Hospital in Boston.

Publication

Sharma R, Llinas R, Urrutia V, Marsh EB. Collaterals predict outcome regardless of time last known normal. Journal of Stroke and Cerebrovascular Diseases 2018;27(4):971-977.
Click to read article



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Cathy Cao, Pharm.D.

Dr. Cathy Cao collaborated with the lab as a pharmacy resident at Johns Hopkins Bayview, exploring the role of international normalized ratio (INR) in predicting ischemia. She is currently the Oncology Pharmacy Specialist at the Dana-Farber Cancer Institute.

Publication

Cao C, Martinelli A, Spoelhof B, Llinas RH, Marsh EB. In potential stroke patients on warfarin, the international normalized ratio predicts ischemia. Cerebrovascular Diseases EXTRA 2017;7(2):111-119.
Click to read article


 

Gabriel Casella, B.A.

As an undergraduate at Johns Hopkins, Gabriel investigated how commonly isolated aphasia was caused by ischemia and found an alternative diagnosis in the majority of cases. He is currently an IRTA Fellow at the National Institute of Aging and applying to MD/PhD programs. 

Publication

Casella G, Llinas RH, Marsh EB. Isolated aphasia in the emergency department: the likelihood of ischemia is low. Clinical Neurology and Neurosurgery 2017;163:24-26.
Click to read article


 

Emma Kaplan, B.A.

Emma worked in the Marsh lab as an undergraduate at Penn, investigating the association between substance abuse and intracranial hemorrhage. She is currently a medical student at the University of Maryland.

Publication

Kaplan EH, Gottesman RF, Llinas RH, Marsh, EB. The association between specific substances of abuse and subcortical intracerebral hemorrhage versus ischemic lacunar infarction. Frontiers in Neurology, 2014;5:174.
Click to read article